Crystallographic Comparison of Manganese- and Iron-Dependent Homoprotocatechuate 2,3-Dioxygenases

The X-ray crystal structures of homoprotocatechuate 2,3-dioxygenases isolated from Arthrobacter globiformis and Brevibacterium fuscum have been determined to high resolution. These enzymes exhibit 83% sequence identity, yet their activities depend on different transition metals, Mn(2+) and Fe(2+), r...

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Main Authors: Vetting, Matthew W., Wackett, Lawrence P., Que, Lawrence, Lipscomb, John D., Ohlendorf, Douglas H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Structural Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC374394/
https://ncbi.nlm.nih.gov/pubmed/15028678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.7.1945-1958.2004
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