Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences
Genetic instability can be induced by unusual DNA structures and sequence repeats. We have previously demonstrated that a large palindrome in the mouse germ line derived from transgene integration is extremely unstable and undergoes stabilizing rearrangements at high frequency, often through deletio...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151008498 |
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