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Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences

Genetic instability can be induced by unusual DNA structures and sequence repeats. We have previously demonstrated that a large palindrome in the mouse germ line derived from transgene integration is extremely unstable and undergoes stabilizing rearrangements at high frequency, often through deletio...

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書目詳細資料
Main Authors: Zhou, Zhi-Hong, Akgün, Ercan, Jasin, Maria
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC37439/
https://ncbi.nlm.nih.gov/pubmed/11459971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151008498
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