Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences

Genetic instability can be induced by unusual DNA structures and sequence repeats. We have previously demonstrated that a large palindrome in the mouse germ line derived from transgene integration is extremely unstable and undergoes stabilizing rearrangements at high frequency, often through deletio...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zhou, Zhi-Hong, Akgün, Ercan, Jasin, Maria
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2001
Schlagworte:	Colloquium Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151008498
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!