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Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences
Genetic instability can be induced by unusual DNA structures and sequence repeats. We have previously demonstrated that a large palindrome in the mouse germ line derived from transgene integration is extremely unstable and undergoes stabilizing rearrangements at high frequency, often through deletio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37439/ https://ncbi.nlm.nih.gov/pubmed/11459971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151008498 |
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