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Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences

Genetic instability can be induced by unusual DNA structures and sequence repeats. We have previously demonstrated that a large palindrome in the mouse germ line derived from transgene integration is extremely unstable and undergoes stabilizing rearrangements at high frequency, often through deletio...

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Hlavní autoři: Zhou, Zhi-Hong, Akgün, Ercan, Jasin, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC37439/
https://ncbi.nlm.nih.gov/pubmed/11459971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151008498
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