Waol A, trans-dihydrowaol A, and cis-dihydrowaol A: polyketide-derived γ-lactones from a Volutella species

An organic extract of a filamentous fungus (MSX 58801), identified as a Volutella sp. (Hypocreales, Ascomycota), displayed moderate cytotoxic activity against NCI-H460 human large cell lung carcinoma. Bioactivity-directed fractionation led to the isolation of three γ-lactones having the furo[3,4-b]p...

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Hauptverfasser: El-Elimat, Tamam, Figueroa, Mario, Raja, Huzefa A., Adcock, Audrey F., Kroll, David J., Swanson, Steven M., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743556/
https://ncbi.nlm.nih.gov/pubmed/23956472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.06.008
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