Resorcylic Acid Lactones with Cytotoxic and NF-κB Inhibitory Activities and Their Structure-activity Relationships

As part of our ongoing investigation of filamentous fungi for anticancer leads, an active fungal extract was identified from the Mycosynthetix library (MSX 63935; related to Phoma sp.). The initial extract exhibited cytotoxic activity against the H460 (human non-small cell lung carcinoma) and SF268...

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Main Authors: Ayers, Sloan, Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Matthew, Susan, Carcache de Blanco, Esperanza J., Shen, Qi, Swanson, Steven M., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111092/
https://ncbi.nlm.nih.gov/pubmed/21513293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np200062x
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