Obionin B: An o-pyranonaphthoquinone decaketide from an unidentified fungus (MSX 63619) from the Order Pleosporales

A fungal extract (MSX 63619), from the Mycosynthetix library of over 50,000 fungi, displayed promising cytotoxicity against a human tumor cell panel. Bioactivity-directed fractionation led to the isolation of an o-pyranonaphthoquinone decaketide, which we termed obionin B (1). The structure of 1 was...

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Auteurs principaux: Ayers, Sloan, Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Shen, Qi, Swanson, Steven M., Wani, Mansukh C., Darveaux, Blaise A., Pearce, Cedric J., Oberlies, Nicholas H.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183506/
https://ncbi.nlm.nih.gov/pubmed/22025810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.07.102
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