Peptaibols, Tetramic Acid Derivatives, Isocoumarins and Sesquiterpenes from a Bionectria sp. (MSX 47401)

An extract of the filamentous fungus Bionectria sp. (MSX 47401) showed both promising cytotoxic activity (>90% inhibition of H460 cell growth at 20 μg/mL) and antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). A bioactivity-directed fractionation study yielded one...

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Hauptverfasser: Figueroa, Mario, Raja, Huzefa, Falkinham, Joseph O., Adcock, Audrey F., Kroll, David J., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736820/
https://ncbi.nlm.nih.gov/pubmed/23806109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np3008842
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