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Rationale for the Development of 2-Aminobenzamide Histone Deacetylase Inhibitors as Therapeutics for Friedreich Ataxia

Numerous studies have pointed to histone deacetylase inhibitors as potential therapeutics for various neurodegenerative diseases, and clinical trials with several histone deacetylase inhibitors have been performed or are underway. However, histone deacetylase inhibitors tested to date are either hig...

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Main Authors: Soragni, Elisabetta, Xu, Chunping, Plasterer, Heather L., Jacques, Vincent, Rusche, James R., Gottesfeld, Joel M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743553/
https://ncbi.nlm.nih.gov/pubmed/22764181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0883073812448533
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