Centrosomal Che-1 Protein Is Involved in the Regulation of Mitosis and DNA Damage Response by Mediating Pericentrin (PCNT)-dependent Chk1 Protein Localization

To combat threats posed by DNA damage, cells have evolved mechanisms, collectively termed DNA damage response (DDR). These mechanisms detect DNA lesions, signal their presence, and promote their repair. Centrosomes integrate G(2)/M checkpoint control and repair signals in response to genotoxic stres...

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Détails bibliographiques
Auteurs principaux: Sorino, Cristina, Bruno, Tiziana, Desantis, Agata, Di Certo, Maria Grazia, Iezzi, Simona, De Nicola, Francesca, Catena, Valeria, Floridi, Aristide, Chessa, Luciana, Passananti, Claudio, Cundari, Enrico, Fanciulli, Maurizio
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743504/
https://ncbi.nlm.nih.gov/pubmed/23798705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465302
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