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PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis

The microtubule-organizing activity of the centrosome oscillates during the cell cycle, reaching its highest level at mitosis. At the onset of mitosis, the centrosome undergoes maturation, which is characterized by a drastic expansion of the pericentriolar matrix (PCM) and a robust increase in micro...

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Detalhes bibliográficos
Main Authors: Lee, Kwanwoo, Rhee, Kunsoo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246884/
https://ncbi.nlm.nih.gov/pubmed/22184200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106093
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