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Oxygen-coupled Redox Regulation of the Skeletal Muscle Ryanodine Receptor/Ca(2+) Release Channel (RyR1): SITES AND NATURE OF OXIDATIVE MODIFICATION
In mammalian skeletal muscle, Ca(2+) release from the sarcoplasmic reticulum (SR) through the ryanodine receptor/Ca(2+)-release channel RyR1 can be enhanced by S-oxidation or S-nitrosylation of separate Cys residues, which are allosterically linked. S-Oxidation of RyR1 is coupled to muscle oxygen te...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743473/ https://ncbi.nlm.nih.gov/pubmed/23798702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.480228 |
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