Detrimental Effect of Class-selective Histone Deacetylase Inhibitors during Tissue Regeneration following Hindlimb Ischemia

Histone deacetylase inhibitors (DIs) are promising drugs for the treatment of several pathologies including ischemic and failing heart where they demonstrated efficacy. However, adverse side effects and cardiotoxicity have also been reported. Remarkably, no information is available about the effect...

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Hlavní autoři: Spallotta, Francesco, Tardivo, Silvia, Nanni, Simona, Rosati, Jessica D., Straino, Stefania, Mai, Antonello, Vecellio, Matteo, Valente, Sergio, Capogrossi, Maurizio C., Farsetti, Antonella, Martone, Julie, Bozzoni, Irene, Pontecorvi, Alfredo, Gaetano, Carlo, Colussi, Claudia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743470/
https://ncbi.nlm.nih.gov/pubmed/23836913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484337
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