Detrimental Effect of Class-selective Histone Deacetylase Inhibitors during Tissue Regeneration following Hindlimb Ischemia

Histone deacetylase inhibitors (DIs) are promising drugs for the treatment of several pathologies including ischemic and failing heart where they demonstrated efficacy. However, adverse side effects and cardiotoxicity have also been reported. Remarkably, no information is available about the effect...

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Detalhes bibliográficos
Main Authors: Spallotta, Francesco, Tardivo, Silvia, Nanni, Simona, Rosati, Jessica D., Straino, Stefania, Mai, Antonello, Vecellio, Matteo, Valente, Sergio, Capogrossi, Maurizio C., Farsetti, Antonella, Martone, Julie, Bozzoni, Irene, Pontecorvi, Alfredo, Gaetano, Carlo, Colussi, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743470/
https://ncbi.nlm.nih.gov/pubmed/23836913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484337
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