Polysialic Acid on Neuropilin-2 Is Exclusively Synthesized by the Polysialyltransferase ST8SiaIV and Attached to Mucin-type O-Glycans Located between the b2 and c Domain

Neuropilin-2 (NRP2) is well known as a co-receptor for class 3 semaphorins and vascular endothelial growth factors, involved in axon guidance and angiogenesis. Moreover, NRP2 was shown to promote chemotactic migration of human monocyte-derived dendritic cells (DCs) toward the chemokine CCL21, a func...

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Main Authors: Rollenhagen, Manuela, Buettner, Falk F. R., Reismann, Marc, Jirmo, Adan Chari, Grove, Melanie, Behrens, Georg M. N., Gerardy-Schahn, Rita, Hanisch, Franz-Georg, Mühlenhoff, Martina
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743467/
https://ncbi.nlm.nih.gov/pubmed/23801331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.463927
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