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Isolation of antibiotic resistance mutations in the rRNA by using an in vitro selection system
Genetic, biochemical, and structural data support an essential role for the ribosomal RNA in all steps of the translation process. Although in vivo genetic selection techniques have been used to identify mutations in the rRNAs that result in various miscoding phenotypes and resistance to known ribos...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC374322/ https://ncbi.nlm.nih.gov/pubmed/15001709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307596101 |
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