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Isolation of antibiotic resistance mutations in the rRNA by using an in vitro selection system

Genetic, biochemical, and structural data support an essential role for the ribosomal RNA in all steps of the translation process. Although in vivo genetic selection techniques have been used to identify mutations in the rRNAs that result in various miscoding phenotypes and resistance to known ribos...

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Bibliografski detalji
Glavni autori: Cochella, Luisa, Green, Rachel
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC374322/
https://ncbi.nlm.nih.gov/pubmed/15001709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307596101
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