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Inactivating Mutations in GT198 in Familial and Early-Onset Breast and Ovarian Cancers
The human GT198 gene (gene symbol PSMC3IP) is located at chromosome 17q21, 470 kb proximal to BRCA1, a locus previously linked to breast and ovarian cancer predisposition. Its protein product (also known as TBPIP and Hop2) has been shown to regulate steroid hormone receptor–mediated gene activation...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743154/ https://ncbi.nlm.nih.gov/pubmed/23946868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913486344 |
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