Inactivating Mutations in GT198 in Familial and Early-Onset Breast and Ovarian Cancers

The human GT198 gene (gene symbol PSMC3IP) is located at chromosome 17q21, 470 kb proximal to BRCA1, a locus previously linked to breast and ovarian cancer predisposition. Its protein product (also known as TBPIP and Hop2) has been shown to regulate steroid hormone receptor–mediated gene activation...

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Hlavní autoři: Peng, Min, Bakker, Janine L., DiCioccio, Richard A., Gille, Johan J.P., Zhao, Hua, Odunsi, Kunle, Sucheston, Lara, Jaafar, Lahcen, Mivechi, Nahid F., Waisfisz, Quinten, Ko, Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2013
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743154/
https://ncbi.nlm.nih.gov/pubmed/23946868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913486344
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