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Activating the Nrf2-mediated antioxidant response element restores barrier function in the alveolar epithelium of HIV-1 transgenic rats

The master transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) regulates the expression of antioxidant and phase II-metabolizing enzymes by activating the antioxidant response element (ARE) and thereby protects cells and tissues from oxidative stress. Pulmonary complications rema...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Xian, Staitieh, Bashar S., Jensen, J. Spencer, Mould, Kara J., Greenberg, Jared A., Joshi, Pratibha C., Koval, Michael, Guidot, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743010/
https://ncbi.nlm.nih.gov/pubmed/23748533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00288.2012
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