Bovine Herpesvirus Tegument Protein VP22 Enhances Thymidine Kinase/Ganciclovir Suicide Gene Therapy for Neuroblastomas Compared to Herpes Simplex Virus VP22

Herpesvirus tegument protein VP22 can enhance the effect of therapeutic proteins in gene therapy, such as thymidine kinase (tk) and p53; however, the mechanism is unclear or controversial. In this study, mammalian expression vectors carrying bovine herpesvirus 1 (BHV-1) VP22 (BVP22) or herpes simple...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Qiu, Zhaohua, Harms, Jerome S., Zhu, Jun, Splitter, Gary A.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2004
Gaiak:	Gene Therapy
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC374295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.8.4224-4233.2004
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