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Bovine Herpesvirus 1 Tegument Protein VP22 Interacts with Histones, and the Carboxyl Terminus of VP22 Is Required for Nuclear Localization

The bovine herpesvirus 1 (BHV-1) UL49 gene encodes a viral tegument protein termed VP22. UL49 homologs are conserved among alphaherpesviruses. Interestingly, the BHV-1 VP22 deletion mutant virus is asymptomatic and avirulent in infected cattle but produces only a slight reduction in titer in vitro....

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Autors principals: Ren, Xiaodi, Harms, Jerome S., Splitter, Gary A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115069/
https://ncbi.nlm.nih.gov/pubmed/11483770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8251-8258.2001
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