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Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations

The persistence leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) despite tyrosine kinase inhibition (TKI) may explain relapse after TKI withdrawal. Here we performed genome-wide transcriptome analysis of highly refined CML and normal stem and progenitor cell populations to identify novel...

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Detalhes bibliográficos
Main Authors: Gerber, Jonathan M., Gucwa, Jessica L., Esopi, David, Gurel, Meltem, Haffner, Michael C., Vala, Milada, Nelson, William G., Jones, Richard J., Yegnasubramanian, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742832/
https://ncbi.nlm.nih.gov/pubmed/23651669
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