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Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

Previous studies have shown that Philadelphia (Ph1) chromosome-positive chronic myeloid leukemia (CML) results from the abnormal expansion at the pluripotent stem cell level of a single clone of hemopoietic cells. Although it seems likely that this is related to the heightened proliferative activity...

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Bibliografiske detaljer
Main Authors: Eaves, A C, Cashman, J D, Gaboury, L A, Kalousek, D K, Eaves, C J
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323940/
https://ncbi.nlm.nih.gov/pubmed/3460093
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