Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

Previous studies have shown that Philadelphia (Ph1) chromosome-positive chronic myeloid leukemia (CML) results from the abnormal expansion at the pluripotent stem cell level of a single clone of hemopoietic cells. Although it seems likely that this is related to the heightened proliferative activity...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Eaves, A C, Cashman, J D, Gaboury, L A, Kalousek, D K, Eaves, C J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323940/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3460093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5306
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