Defective RNA Replication and Late Gene Expression in Temperature-Sensitive Influenza Viruses Expressing Deleted Forms of the NS1 Protein

Influenza A virus mutants expressing C-terminally deleted forms of the NS1 protein (NS1-81 and NS1-110) were generated by plasmid rescue. These viruses were temperature sensitive and showed a small plaque size at the permissive temperature. The accumulation of virion RNA in mutant virus-infected cel...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Falcón, Ana M., Marión, Rosa M., Zürcher, Thomas, Gómez, Paulino, Portela, Agustín, Nieto, Amelia, Ortín, Juan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC374278/
https://ncbi.nlm.nih.gov/pubmed/15047804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.3880-3888.2004
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk