Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: Relevance to lung cancer

Cytoskeletal and focal adhesion abnormalities are observed in several types of cancer, including lung cancer. We have previously reported that paxillin (PXN) was mutated, amplified, and overexpressed in a significant number of lung cancer patient samples, that PXN protein was upregulated in more adv...

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Hlavní autoři: Kawada, Ichiro, Hasina, Rifat, Lennon, Frances E, Bindokas, Vytautas P, Usatyuk, Peter, Tan, Yi-Hung C, Krishnaswamy, Soundararajan, Arif, Qudsia, Carey, George, Hseu, Robyn D, Robinson, Matthew, Tretiakova, Maria, Brand, Toni M, Iida, Mari, Ferguson, Mark K, Wheeler, Deric L, Husain, Aliya N, Natarajan, Viswanathan, Vokes, Everett E, Singleton, Patrick A, Salgia, Ravi
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742497/
https://ncbi.nlm.nih.gov/pubmed/23792636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25091
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