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Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function

Abstract. Paxillin is a multifunctional and multidomain focal adhesion adaptor protein. It serves as an important scaffolding protein at focal adhesions by recruiting and binding to structural and signaling molecules. Paxillin tyrosine phosphorylation at Y31 and Y118 is important for paxillin redist...

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Bibliografske podrobnosti
izdano v:Pulm Circ
Main Authors: Fu, Panfeng, Usatyuk, Peter V., Jacobson, Jeffrey, Cress, Anne E., Garcia, Joe G. N., Salgia, Ravi, Natarajan, Viswanathan
Format: Artigo
Jezik:Inglês
Izdano: University of Chicago Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671736/
https://ncbi.nlm.nih.gov/pubmed/26697169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/683693
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