MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes

The myelination of axons is a crucial step during vertebrate central nervous system (CNS) development, allowing for rapid and energy efficient saltatory conduction of nerve impulses. Accordingly, the differentiation of oligodendrocytes, the myelinating cells of the CNS, and their expression of myeli...

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Главные авторы: Bujalka, Helena, Koenning, Matthias, Jackson, Stacey, Perreau, Victoria M., Pope, Bernard, Hay, Curtis M., Mitew, Stanlislaw, Hill, Andrew F., Lu, Q. Richard, Wegner, Michael, Srinivasan, Rajini, Svaren, John, Willingham, Melanie, Barres, Ben A., Emery, Ben
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742440/
https://ncbi.nlm.nih.gov/pubmed/23966833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001625
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