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Dissection and Design of Yeast Prions

Many proteins can misfold into β-sheet-rich, self-seeding polymers (amyloids). Prions are exceptional among such aggregates in that they are also infectious. In fungi, prions are not pathogenic but rather act as epigenetic regulators of cell physiology, providing a powerful model for studying the me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Osherovich, Lev Z, Cox, Brian S, Tuite, Mick F, Weissman, Jonathan S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC374241/
https://ncbi.nlm.nih.gov/pubmed/15045026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020086
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