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Dissection and Design of Yeast Prions

Many proteins can misfold into β-sheet-rich, self-seeding polymers (amyloids). Prions are exceptional among such aggregates in that they are also infectious. In fungi, prions are not pathogenic but rather act as epigenetic regulators of cell physiology, providing a powerful model for studying the me...

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Detalles Bibliográficos
Main Authors: Osherovich, Lev Z, Cox, Brian S, Tuite, Mick F, Weissman, Jonathan S
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC374241/
https://ncbi.nlm.nih.gov/pubmed/15045026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020086
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