The mRNA Binding Proteins HuR and Tristetraprolin Regulate Cyclooxygenase 2 Expression During Colon Carcinogenesis

BACKGROUND & AIMS: During tumorigenesis, loss of rapid messenger RNA (mRNA) decay allows for overexpression of cancer-associated genes. The RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP) bind AU-rich elements in the 3′ untranslated region of many cancer-associated mRNAs and ta...

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Main Authors: Young, Lisa E., Sanduja, Sandhya, Bemis–Standoli, Kristi, Pena, Edsel A., Price, Robert L., Dixon, Dan A.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742387/
https://ncbi.nlm.nih.gov/pubmed/19208339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.01.010
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