Cytosolic Phospholipase A(2)α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation

The role of Group IVA cytosolic phospholipase A(2) (cPLA(2)α) activation in regulating macrophage transcriptional responses to Candida albicans infection was investigated. cPLA(2)α releases arachidonic acid for the production of eicosanoids. In mouse resident peritoneal macrophages, prostacyclin, pr...

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Hauptverfasser: Suram, Saritha, Silveira, Lori J., Mahaffey, Spencer, Brown, Gordon D., Bonventre, Joseph V., Williams, David L., Gow, Neil A. R., Bratton, Donna L., Murphy, Robert C., Leslie, Christina C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742295/
https://ncbi.nlm.nih.gov/pubmed/23950842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069002
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