Prostaglandins from Cytosolic Phospholipase A(2)α/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages

In Candida albicans-infected resident peritoneal macrophages, activation of group IVA cytosolic phospholipase A(2) (cPLA(2)α) by calcium- and mitogen-activated protein kinases triggers the rapid production of prostaglandins I(2) and E(2) through cyclooxygenase (COX)-1 and regulates gene expression b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yun, Bogeon, Lee, HeeJung, Jayaraja, Sabarirajan, Suram, Saritha, Murphy, Robert C., Leslie, Christina C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807289/
https://ncbi.nlm.nih.gov/pubmed/26841868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714873
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