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Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A(2)α in Regulating Interfacial Kinetics and Binding and Cellular Function
Group IVA cytosolic phospholipase A(2) (cPLA(2)α) is regulated by phosphorylation and calcium-induced translocation to membranes. Immortalized mouse lung fibroblasts lacking endogenous cPLA(2)α (IMLF(-/-)) were reconstituted with wild type and cPLA(2)α mutants to investigate how calcium, phosphoryla...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666612/ https://ncbi.nlm.nih.gov/pubmed/19176526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807299200 |
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