Cytosolic Phospholipase A(2)α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation

The role of Group IVA cytosolic phospholipase A(2) (cPLA(2)α) activation in regulating macrophage transcriptional responses to Candida albicans infection was investigated. cPLA(2)α releases arachidonic acid for the production of eicosanoids. In mouse resident peritoneal macrophages, prostacyclin, pr...

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Detalhes bibliográficos
Main Authors: Suram, Saritha, Silveira, Lori J., Mahaffey, Spencer, Brown, Gordon D., Bonventre, Joseph V., Williams, David L., Gow, Neil A. R., Bratton, Donna L., Murphy, Robert C., Leslie, Christina C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742295/
https://ncbi.nlm.nih.gov/pubmed/23950842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069002
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