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Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR

We propose a kinetic model for the activation of the las regulon in the opportunistic pathogen Pseudomonas aeruginosa. The model is based on in vitro data and accounts for the LasR dimerization and consecutive activation by binding of two OdDHL signal molecules. Experimentally, the production of the...

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Autors principals: Claussen, Anetta, Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, Martin, Ferkinghoff-Borg, Jesper, Sams, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742191/
https://ncbi.nlm.nih.gov/pubmed/23807499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140713360
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