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Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline

RNA polymerase II (Pol II) elongation in metazoans is thought to require phosphorylation of serine 2 (Ser2-P) of the Pol II C-terminal domain (CTD) by the P-TEFb complex, CDK-9/cyclin T. Another Ser2 kinase complex, CDK-12/cyclin K, which requires upstream CDK-9 activity has been identified in Droso...

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Autors principals: Bowman, Elizabeth Anne, Bowman, Christopher Ray, Ahn, Jeong H., Kelly, William G.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742150/
https://ncbi.nlm.nih.gov/pubmed/23903194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095778
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