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The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic function

After neuronal injury or death glial cells become reactive, exhibiting dramatic changes in morphology and patterns of gene expression and ultimately engulfing neuronal debris. Rapid clearance of degenerating neuronal material is thought to be crucial for suppression of inflammation and promotion of...

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Detalhes bibliográficos
Main Authors: MacDonald, J M, Doherty, J, Hackett, R, Freeman, M R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741495/
https://ncbi.nlm.nih.gov/pubmed/23618811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.30
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