Clonal Dissemination, Emergence of Mutator Lineages and Antibiotic Resistance Evolution in Pseudomonas aeruginosa Cystic Fibrosis Chronic Lung Infection

Chronic respiratory infection by Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF). We investigated the interplay between three key microbiological aspects of these infections: the occurrence of transmissible and persistent strains, the emergence of variants with enhanced...

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Main Authors: López-Causapé, Carla, Rojo-Molinero, Estrella, Mulet, Xavier, Cabot, Gabriel, Moyà, Bartolomé, Figuerola, Joan, Togores, Bernat, Pérez, José L., Oliver, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741393/
https://ncbi.nlm.nih.gov/pubmed/23951065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071001
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