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Genetic Variation in the Base Excision Repair Pathway, Environmental Risk Factors, and Colorectal Adenoma Risk

Cigarette smoking, high alcohol intake, and low dietary folate levels are risk factors for colorectal adenomas. Oxidative damage caused by these three factors can be repaired through the base excision repair pathway (BER). We hypothesized that genetic variation in BER might modify colorectal adenoma...

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Détails bibliographiques
Auteurs principaux: Corral, Roman, Lewinger, Juan Pablo, Joshi, Amit D., Levine, A. Joan, Vandenberg, David J., Haile, Robert W., Stern, Mariana C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741365/
https://ncbi.nlm.nih.gov/pubmed/23951112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071211
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