Genetic Variation in the Base Excision Repair Pathway, Environmental Risk Factors, and Colorectal Adenoma Risk

Cigarette smoking, high alcohol intake, and low dietary folate levels are risk factors for colorectal adenomas. Oxidative damage caused by these three factors can be repaired through the base excision repair pathway (BER). We hypothesized that genetic variation in BER might modify colorectal adenoma...

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Detalhes bibliográficos
Main Authors: Corral, Roman, Lewinger, Juan Pablo, Joshi, Amit D., Levine, A. Joan, Vandenberg, David J., Haile, Robert W., Stern, Mariana C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741365/
https://ncbi.nlm.nih.gov/pubmed/23951112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071211
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