Us3 Kinase Encoded by Herpes Simplex Virus 1 Mediates Downregulation of Cell Surface Major Histocompatibility Complex Class I and Evasion of CD8(+) T Cells

Detection and elimination of virus-infected cells by CD8(+) cytotoxic T lymphocytes (CTLs) depends on recognition of virus-derived peptides presented by major histocompatibility complex class I (MHC-I) molecules on the surface of infected cells. In the present study, we showed that inactivation of t...

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Detalhes bibliográficos
Main Authors: Imai, Takahiko, Koyanagi, Naoto, Ogawa, Ryo, Shindo, Keiko, Suenaga, Tadahiro, Sato, Ayuko, Arii, Jun, Kato, Akihisa, Kiyono, Hiroshi, Arase, Hisashi, Kawaguchi, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741198/
https://ncbi.nlm.nih.gov/pubmed/23951282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072050
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