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Herpes simplex virus-1 evasion of CD8(+) T cell accumulation contributes to viral encephalitis

Herpes simplex virus–1 (HSV-1) is the most common cause of sporadic viral encephalitis, which can be lethal or result in severe neurological defects even with antiviral therapy. While HSV-1 causes encephalitis in spite of HSV-1–specific humoral and cellular immunity, the mechanism by which HSV-1 eva...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Koyanagi, Naoto, Imai, Takahiko, Shindo, Keiko, Sato, Ayuko, Fujii, Wataru, Ichinohe, Takeshi, Takemura, Naoki, Kakuta, Shigeru, Uematsu, Satoshi, Kiyono, Hiroshi, Maruzuru, Yuhei, Arii, Jun, Kato, Akihisa, Kawaguchi, Yasushi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617679/
https://ncbi.nlm.nih.gov/pubmed/28891812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92931
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