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GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses
Within the TGF-β superfamily, there are approximately forty ligands divided into two major branches: the TGF-β/Activin/Nodal ligands and the BMP/GDF ligands. We studied the ligand GDF3 and found that it inhibits signaling by its co-family members, the BMPs; however, GDF3 has been described by others...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740937/ https://ncbi.nlm.nih.gov/pubmed/18823971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.006 |
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