Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis

Macrophage migration inhibitory factor (MIF), an innate cytokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation but may be crucial for controlling infection. We explored the role of variant MIF alleles in tuberculosis. In a Ugandan cohort, genetic low ex...

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Bibliografiske detaljer
Main Authors: Das, Rituparna, Koo, Mi-Sun, Kim, Bae Hoon, Jacob, Shevin T., Subbian, Selvakumar, Yao, Jie, Leng, Lin, Levy, Rebecca, Murchison, Charles, Burman, William J., Moore, Christopher C., Scheld, W. Michael, David, John R., Kaplan, Gilla, MacMicking, John D., Bucala, Richard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740876/
https://ncbi.nlm.nih.gov/pubmed/23882081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301128110
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