Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis

Macrophage migration inhibitory factor (MIF), an innate cytokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation but may be crucial for controlling infection. We explored the role of variant MIF alleles in tuberculosis. In a Ugandan cohort, genetic low ex...

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Detalhes bibliográficos
Main Authors: Das, Rituparna, Koo, Mi-Sun, Kim, Bae Hoon, Jacob, Shevin T., Subbian, Selvakumar, Yao, Jie, Leng, Lin, Levy, Rebecca, Murchison, Charles, Burman, William J., Moore, Christopher C., Scheld, W. Michael, David, John R., Kaplan, Gilla, MacMicking, John D., Bucala, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740876/
https://ncbi.nlm.nih.gov/pubmed/23882081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301128110
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