Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis

Macrophage migration inhibitory factor (MIF), an innate cytokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation but may be crucial for controlling infection. We explored the role of variant MIF alleles in tuberculosis. In a Ugandan cohort, genetic low ex...

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Autori principali: Das, Rituparna, Koo, Mi-Sun, Kim, Bae Hoon, Jacob, Shevin T., Subbian, Selvakumar, Yao, Jie, Leng, Lin, Levy, Rebecca, Murchison, Charles, Burman, William J., Moore, Christopher C., Scheld, W. Michael, David, John R., Kaplan, Gilla, MacMicking, John D., Bucala, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740876/
https://ncbi.nlm.nih.gov/pubmed/23882081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301128110
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