Interphase cytofission maintains genomic integrity of human cells after failed cytokinesis

In cell division, cytokinesis is tightly coupled with mitosis to maintain genomic integrity. Failed cytokinesis in humans can result in tetraploid cells that can become aneuploid and promote cancer. However, the likelihood of aneuploidy and cancer after a failed cytokinesis event is unknown. Here we...

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Bibliografiske detaljer
Main Authors: Choudhary, Alka, Lera, Robert F., Martowicz, Melissa L., Oxendine, Kim, Laffin, Jennifer J., Weaver, Beth A., Burkard, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740861/
https://ncbi.nlm.nih.gov/pubmed/23878225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308203110
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