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Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer

The receptor tyrosine kinases Axl and Mer, belonging to the Tyro3, Axl and Mer (TAM) receptor family, are expressed in a number of tumor cells and have well-characterized oncogenic roles. The therapeutic targeting of these kinases is considered an anticancer strategy, and various inhibitors are curr...

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Autores principales: Bosurgi, Lidia, Bernink, Jochem H., Delgado Cuevas, Victor, Gagliani, Nicola, Joannas, Leonel, Schmid, Edward T., Booth, Carmen J., Ghosh, Sourav, Rothlin, Carla V.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740859/
https://ncbi.nlm.nih.gov/pubmed/23878224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302507110
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