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Dietary gluten triggers concomitant activation of CD4(+) and CD8(+) αβ T cells and γδ T cells in celiac disease

Celiac disease is an intestinal autoimmune disease driven by dietary gluten and gluten-specific CD4(+) T-cell responses. In celiac patients on a gluten-free diet, exposure to gluten induces the appearance of gluten-specific CD4(+) T cells with gut-homing potential in the peripheral blood. Here we sh...

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Detalhes bibliográficos
Main Authors: Han, Arnold, Newell, Evan W., Glanville, Jacob, Fernandez-Becker, Nielsen, Khosla, Chaitan, Chien, Yueh-hsiu, Davis, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740842/
https://ncbi.nlm.nih.gov/pubmed/23878218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311861110
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